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New FDA Guidance Impacts the CAR-T Industry
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In January, the FDA published, “Considerations for the Development of Chimeric Antigen Receptor (CAR) T Cell Products: Guidance for Industry.” To find out how this guidance impacts the CAR-T industry, GEN talked with Klara Sochorová, PhD, senior quality compliance manager at SCTbio, which is a contract development and manufacturing organization (CDMO) based in Prague...
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AI and Laser Tech Automate Rapid Sorting and Analysis of Live Cells
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The ability to isolate specific cell types without impairing cell vitality is also necessary to advance pharmaceutical research. In response to this need, the Fraunhofer Institutes of Laser Technology (ILT) and Production Technology (IPT) developed an AI-assisted tool that automatically sorts and isolates living cells from samples using a high-throughput process...
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Beckman Coulter Life Sciences Revolutionizes Nanoparticle Analysis
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Beckman Coulter Life Sciences, a global leader in laboratory automation and innovation and a subsidiary of Danaher Corporation (NYSE: DHR), continues to lead the way with first-to-market concepts with the launch of the CytoFLEX nano Flow Cytometer – the first purpose-built nanoscale flow cytometer for research use only that enables detection to at least 40 nm,* enabling 30-50%...
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Distinct cd16a Features on Human NK Cells Observed by Flow Cytometry Correlate With Increased ADCC
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Natural killer (NK) cells destroy tissue that have been opsonized with antibodies. Strategies to generate or identify cells with increased potency are expected to enhance NK cell-based immunotherapies. We previously generated NK cells with increased antibody-dependent cell mediated cytotoxicity (ADCC) following treatment with kifunensine, an inhibitor targeting mannosidases early in the N-glycan...
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