Intravital Imaging to Study Cancer Progression and Metastasis

www.nature.com

Navigation through the bulk tumor, entry into the blood vasculature, survival in the circulation, exit at distant sites and resumption of proliferation are all steps necessary for tumor cells...

Distinct Immunological Signatures Discriminate Severe COVID-19 from Non-sars-Cov-2-Driven Critical Pneumonia

www.cell.com

Immune profiling of COVID-19 patients has identified numerous alterations in both innate and adaptive immunity. Here, we compared the immune profile of severe COVID-19 with non-SARS-CoV-2...

Mass Versus Personalized Medicine Against COVID-19 in the “System Sciences” Era

onlinelibrary.wiley.com

The importance of personalized/precision medicine for targeted therapies and improved outcomes both in terms of efficacy and safety in health care is by now grounded. We here discuss the current landscape of personalized medicine approaches against SARS-CoV-2...

Mantle Cell Lymphoma (MCL) Flow Cytometry: Link to Several Case Studies

wiki.clinicalflow.com

Definition MCL is a subtype of CD5+ B-cell lymphoma. There are only about 15,000 patients presently in the U.S though the prevalence seems to be somewhat higher in Europe. It is difficult to treat and seldom considered cured, Median survival times...

Intraoperative Flow Cytometry for the Evaluation of Meningioma Grade

www.mdpi.com

Meningiomas are the most frequent central nervous system tumors in adults. The majority of these tumors are benign. Nevertheless, the intraoperative identification of meningioma grade is important for modifying surgical strategy in order...

A Guideline for the Appropriate Recognition of Shared Resource Laboratories in Publication

onlinelibrary.wiley.com

The issue of what level of contribution warrants authorship, determining a fair order of authors and when and whom to acknowledge in publications is often a cause of debate. To avoid SRLs and SRL staff scientist contributions going unnoticed...

Single Tube Multiparametric Flow-Cytometry Predicts Treatment Response in Leukemia

meridian.allenpress.com

A single-tube eight-color multiparametric flow cytometry (MFC) panel has good sensitivity for minimal/measurable residual disease (MRD) and excellent prediction for survival among patients with B-cell...

Imaging Mass Cytometry in Immuno-Oncology

link.springer.com

In situ profiling of the tumor-immune microenvironment (TiME) requires the ability to co-localize and detect multiple proteins simultaneously. Imaging mass cytometry (IMC), using the...

Where Diagnosis for Myelodysplastic Neoplasms (MDS) Stands Today and Where It Will Go: The Role of Flow Cytometry in Evaluation of MDS

onlinelibrary.wiley.com

Myelodysplastic neoplasms (MDS) are clonal hematopoietic neoplasms defined by cytopenias and morphologic dysplasia. This definition distinguishes MDS from CHIP and CCUS wherein a patient...

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