High-Dimensional Multi-Pass Flow Cytometry via Spectrally Encoded Cellular Barcoding

www.ncbi.nlm.nih.gov

Advances in immunology, immuno-oncology, drug discovery and vaccine development demand improvements in the capabilities of flow cytometry to allow it to measure more protein markers per cell...

Signal Amplification by Cyclic Extension Enables High-Sensitivity Single-Cell Mass Cytometry

www.nature.com

Mass cytometry uses metal-isotope-tagged antibodies to label targets of interest, which enables simultaneous measurements of ~50 proteins or protein modifications in millions of single cells, but its...

Implementation of Flow Cytometry Testing on Rare Matrix Samples: Special Considerations and Best Practices When the Sample Is Unique or Difficult to Obtain

onlinelibrary.wiley.com

This document is the result of a collaboration subject matter experts from a diverse range of backgrounds and seeks to provide best practice consensus guidance regarding these types of...

COPAS VISION Large Particle (10-1500 µm) Flow Cytometry with Imaging

Sponsored

Automated analysis, dispensing and image capture of viable multicellular organisms, cell clusters, bead-like particles and other samples that are too large / fragile for traditional flow cytometers.

SANTO: A Coarse-To-Fine Alignment and Stitching Method for Spatial Omics

pubmed.ncbi.nlm.nih.gov

With the flourishing of spatial omics technologies, alignment and stitching of slices becomes indispensable to decipher a holistic view of 3D molecular profile. However, existing alignment and stitching methods are unpractical to process...

Fourier-Domain-Compressed Optical Time-Stretch Quantitative Phase Imaging Flow Cytometry

opg.optica.org

Optical time-stretch (OTS) imaging flow cytometry offers a promising solution for high-throughput and high-precision cell analysis due to its capabilities of high-speed, high-quality, and continuous imaging. Compressed sensing (CS) makes...

OMIPs—Orchestrating Multiplexity in Polychromatic Science

onlinelibrary.wiley.com

Cytometry is spearheading advances in quantitative cell based research with its technological emphasis on flow and image based cytometric assays. However, it is not only the innovative technologies but also innovations in increasing the...

Single-Cell Mass Cytometry in Immunological Skin Diseases

www.frontiersin.org

Immune-related skin diseases represent a collective of dermatological disorders intricately linked to dysfunctional immune system processes. These conditions are primarily characterized by an immoderate activation of the immune system or...

The Highest Sensitivity over the Most Channels – in a Smaller Footprint.

Sponsored

Meet the demand for high-performance results with Hamamatsu’s spectral detection solutions for high-parameter experiments. Our PMTs and solid state detectors deliver flexible design of many channels.

Single-Cell Mass Cytometry Gets Boost from Signal Amplification Technology

www.genengnews.com

The newer approach of mass cytometry allows the simultaneous quantification of 50 proteins in single cells through the use of antibodies linked to non-radioactive isotopes of...

Design and Validation of Novel Flow Cytometry Panels to Analyze a Comprehensive Range of Peripheral Immune Cells in Mice

www.frontiersin.org

The use of flow cytometry in mice is constrained by several factors, including the limited availability of mouse-specific antibodies and the need to work with small volumes of peripheral blood...

Morphological and Molecular Preservation Through Universal Preparation of Fresh-Frozen Tissue Samples for Multimodal Imaging Workflows

www.nature.com

The landscape of tissue-based imaging modalities is constantly and rapidly evolving. While formalin-fixed, paraffin-embedded material is still useful for histological imaging, the fixation process...

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