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Flow Cytometry Uncovers Predictive Biomarker for Severe COVID
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Using image-based flow cytometry, researchers at the Technical University of Munich (TUM) identified a biomarker for predicting how serious a COVID-19 infection will be. They also developed a rapid test for assessing a patient’s risk of severe COVID-19 infection. The ability to determine the potential gravity of a COVID infection will help physicians determine the most effective treatment for these patients...
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High-Dimensional Multi-Pass Flow Cytometry via Spectrally Encoded Cellular Barcoding
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Multipass high-dimensional flow cytometry. Barcoding cells with microparticles that emit near-infrared laser enables the use of flow cytometry to track the dynamics of single cells by using more markers and fewer colours. The authors describe multi-pass high-dimensional flow cytometry, a method leveraging cellular barcoding via microparticles emitting near-infrared laser light to track and...
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Prevention of Respiratory Virus Transmission by Resident Memory CD8+ T Cells
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An ideal vaccine not only attenuates virus growth and disease in infected individuals but also reduces the spread of infections in the population, thereby generating herd immunity. While this strategy has proven successful by generating humoral immunity to measles, yellow fever and polio, many respiratory viruses evolve to evade pre-existing antibodies 1. One approach for improving the breadth of antiviral...
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